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Although previous studies have used nano-fluorescent probes to detect the cellular delivery efficiency of oligonucleotide molecules, 403,457,575 more pharmacokinetic data on biodistribution, immune compatibility, and toxicity are needed for clinical translation and practical therapeutic application of these systems

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Pentagalloyl Glucose, a Major Compound in Mango Seed Kernel, Exhibits Distinct Gastroprotective Effects in IndomethacinInduced Gastropathy in Rats Via Modulating the no/Enos/Inos Signaling Pathway. Frontiers in Pharmacology 13: 800986

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doi: 10.1053/j.gastro.2020.05.048 Summary Keywords ozone therapy, immune response, SARS-CoV-2, COVID-19, microbiome, antioxidant, cytokine storm, anti-inflammatory Citation Cenci A, Macchia I, La Sorsa V, Sbarigia C, Di Donna V and Pietraforte D (2022) Mechanisms of Action of Ozone Therapy in Emerging Viral Diseases: Immunomodulatory Effects and Therapeutic Advantages With Reference to SARS-CoV-2