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SGLT2 Inhibitors as Calorie Restriction Mimetics: Insights on Longevity Pathways and Age-Related Diseases

The molecular hallmarks of epigenetic control

As a backup fuel for the brain, ketone bodies can cross the bloodbrain barrier, thereby improving the function of energy-starved neurons

doi: 10.1038/nrclinonc.2016.60 31 KoppulaPZhuangLGanB

& Alaei, S

The combined neuroprotective, synaptogenic, and neurogenic mechanisms activated by these compounds encourage the possibility that they may offer a treatment option for neurodegenerative and neuro-traumatic disorders beyond AD
