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Heise T, DeVries JH, Urva S, Li J, Pratt EJ, Thomas MK, et al

We identified several TFs with new roles in cortical neurogenesis, including ZNF219 previously uncharacterizedthat represses neural differentiation and NR2E1 and ARX that have opposing roles in regulating RG lineage plasticity and progression across developmental stages

J Thorac Cardiovasc Surg 154(4):1349-1351, 2017

And then you're going to have a whole bunch of side effects

A.MoorhouseA

IGF-1 plays a central role in tumor development by stimulating proliferation and inhibiting apoptosis in cancer cells. Pollak, Nature Reviews Cancer Acromegaly-Like Symptoms (Rare) In extremely high or prolonged dosesespecially when stacked with HGHIGF-1 may contribute to: Bone thickening (jaw, forehead, hands) Enlarged soft tissue Headaches or carpal tunnel symptoms These side effects mimic acromegaly , a condition caused by excessive GH/IGF-1 signaling