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10.1016/j.mce.2016.04.024 Mol

Sertoli cells have a functional NALP3 inflammasome that can modulate autophagy and cytokine production

doi: 10.3389/fphar.2014.00065 15 Dal LagoA.GalantiF.MirielloD.MarcocciaA.MassimianiM.CampagnoloL.et al

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Predisposition to infection is mediated by gene mutations encoding IFNR1, STAT1, STAT3, CD40L, or GATA2 (responsible for type 1 immune response), IFN neutralizing autoantibodies (191)

IR is closely related to the inflammatory response and is now considered a chronic subclinical inflammatory process [60]
