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The standard curve plasma samples were then stored at -20C and further processed alongside the pharmacokinetic study samples according to the method described above
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Unfortunately, current senolytics exhibit high variability in efficacy, depending on the type of cell undergoing senescence [141]
The melatonin pineal daily rhythm is determined by the conversion of 5HT to NAS under sympathetic control (Figure 2)
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Sonne, N., Karsdal, M
