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Findings from this study showed that chronic ICV leptin infusion, at rates that did not increase plasma leptin levels, restored normoglycemia in streptozotocin (STZ)induced diabetic rats and reduced blood glucose concentration in the conjoined parabiotic rats infused with vehicle

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investigated various dietary patterns, including a diet low in carbohydrates, with restricted FODMAPs, no gluten, and emphasizing anti-inflammatory properties, and MD, and found that the MD was particularly beneficial for IBD symptom enhancement and mucosal healing (178)