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The viability of the treated cells was calculated relative to the untreated cells (controls) as follows: where F represent fluorescence treated cells, D represent fluorescence of control

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A single band at 68 kDa was excised from the gel, digested with trypsin and analysed by matrix-assisted laser desorption/ionizationtime of flight mass spectrometry (MS) at the proteomics facility at the Sanford-Burnham Medical Research Institute