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Another plant with well-known neuroprotective effects against neuropsychiatric disorders is turmeric ( Curcuma longa ), whose properties can be mainly attributed to curcumin

Parkinsonism was also linked with dementia pugilistica in select cases

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The pulmonary hypertension findings deserve special attention

Serious Side Effects: Hypersensitivity or anaphylaxis (extremely rare), bronchospasm

Reactions were performed with 0.5 M catechol substrate COMT-S01, 1 M radiolabelled S-adenosyl-L-[methyl-3H] methionine (SAM) co-substrate, and recombinant human COMT enzyme
