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Moving forward, the inclusion of core outcome measures in MCADD therapeutic clinical trials would be of great value, particularly given the challenges of gathering large cohorts for rare diseases such as MCADD

Significantly decreased liver -hydroxybutyrate levels from 0.694 0.083 to 0.383 0.087 moles/g wet weight in rats fed a 30% fat plus 20% 1,3-butanediol diet

National Academies Press

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Obesity and male hypogonadism: Tales of a vicious cycle

Moreover, synthetic lysine plays a role in pharmaceutical formulations, particularly in products designed to treat cold sores and other lysine-deficient conditions