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Fielding CA, Sabberwal P, Williamson JC, Greenwood E, Crozier T, Zelek W, et al

This includes the release of pro-inflammatory cytokines like IL-6 and TNF-alpha, which can cross the blood-brain barrier and cause severe neuroinflammation

Not intended for pregnant and lactating women

Specific polymorphisms, such as CLOCK rs11133373, PER3 VNTR, and MTNR1A rs2119882, have been associated with differential susceptibility to circadian misalignment and cancer risk 270 , hence they can be used for risk stratification purposes

Notably, only dermal papilla cells exhibited a germ-like structure, whereas spherical fibroblasts and keratinocytes elongated in a unidirectional manner