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Pasut G, Veronese F (2007) Polymerdrug conjugation, recent achievements and general strategies

Macromolecule Content Total Structure Weight: 24.19 kDa Atom Count: 1,657 Modeled Residue Count: 185 Deposited Residue Count: 208 Unique protein chains: 1 Experimental Data Method: X-RAY DIFFRACTION Resolution: 2.10 R-Value Free: 0.205 (Depositor), 0.208 (DCC) R-Value Work: 0.156 (Depositor), 0.165 (DCC) R-Value Observed: 0.158 (Depositor) Unit Cell : Software Package: Deposition Data Released Date: 2006-07-25 Deposition Author(s): Johansson, C., Kavanagh, K.L., Rojkova, A., Gileadi, O., von Delft, F., Arrowsmith, C., Weigelt, J., Sundstrom, M., Edwards, A., Oppermann, U., Structural Genomics Consortium (SGC) Revision History (Full details and data files) Version 1.0: 2006-07-25 Type: Initial release Version 1.1: 2008-05-01 Changes: Version format compliance Version 1.2: 2011-07-13 Changes: Advisory, Derived calculations, Version format compliance Version 1.3: 2018-01-31 Changes: Structure summary Version 1.4: 2021-10-20 Changes: Database references, Derived calculations Version 1.5: 2023-08-30 Changes: Data collection, Refinement description

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This research benefited from use of the Technion Center of Structural Biology facility of the Lorry I

For the authorized uses, although limited scientific information is available, based on the totality of the scientific evidence available to date, it is reasonable to believe that the Pfizer-BioNTech COVID-19 Vaccine and COMIRNATY (COVID-19 Vaccine, mRNA) may be effective for the prevention of COVID-19 in individuals as specified in the Full EUA Prescribing Information

Hong Kong Preclinical studies have demonstrated that FOXO4-DRI can improve tissue regeneration, enhance organ function, and extend lifespan in animal models