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Crucially, unlike steroid hormones, which persist in the body for an extended duration, peptides have a short half-life, contributing to a favorable safety profile

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There have also been instances of pharmacies using different salt forms of semaglutide, which have not been approved by the FDA and whose safety and efficacy are unknown. Manne-Goehler said that many reports have suggested that the current compounded GLP-1s have a higher number of severe side effects