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At increasing concentrations of the drugs tested, there was a significant dose-dependent reduction of Ki67 mRNA expression (Figure 1a)

robust human clinical trial evidence remains limited

In a murine model, Chen et al

Other safety switches that are effective include the herpes simplex thymidine kinase, epidermal growth factor receptor, and CD20, inducing T-cell death upon exposure to ganciclovir, cetuximab, and rituximab, respectively []

Insights into ferroptosis, a novel target for the therapy of cancer
J Clin Neurosci 12(4):426428
