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Pharmacological preconditioning with sildenafil: Basic mechanisms and clinical implications

In the study, administration of CUR (100 mg/kg) effectively alleviated cisplatin-induced cognitive deficits by regulating apoptosis-related proteins, promoting autophagy, and initiating neurogenesis and synaptogenesis

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JAMA Oncology 10(11), 2024

In addition to its direct effects on the cardiovascular system, HO-1 may also indirectly affect the occurrence and development of cardiovascular diseases in diabetes by regulating other biological processes
