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In individual cases where the severity and frequency of the seizure disorder are such that the removal of medication does not pose a serious threat to the patient, discontinuation of the drug may be considered prior to and during pregnancy, although it cannot be said with any confidence that even minor seizures do not pose some hazard to the developing embryo or fetus [see Boxed Warning and Use in Specific Populations (8.1)]

Toxins 11, 11
et al., 2017

Esto tambin explica el aumento de las necesidades de este compuesto hasta niveles difciles de cubrir con la dieta en los deportistas profesionales y aficionados

Kyotakoze, H

But, it is important to keep in mind that excessive consumption or high dosages may lead to side effects