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Wadman, R

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Seifar F, Khalili M, Khaledyan H, Amiri Moghadam S, Izadi A, Azimi A, et al

T.DuY.et al

Lesniewska B, Miskowiak B, Nowak M, Malendowicz LK

As a core metabolic product, lactate may promote the release of inflammatory mediators (e.g., IL-6, TNF-) by activating the TGF- signaling pathway, while enhancing NF-B pathway activity to exacerbate local inflammatory infiltration in lung tissue but this direct activation has not been demonstrated in COPD airway cells