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Conclusions : It appears that 500 M and pathophysiological concentrations (800 M) of UA induce antioxidant cell response in J744A.1 macrophages proved by the indicative elevation GCL, GPx1, GR, and GS transcription

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Oxidative phosphorylation captures this energy via the synthesis of the high-energy phosphate of ATP

62 Additionally, GSTs contribute to the regulation of cellular redox balance by modulating reactive oxygen species and reactive nitrogen species levels through the conjugation of GSH to oxidized molecules

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