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However, the timing of these changes differed

V.ManosE

10.1371/journal.pone.0004253 PLoS One 106 PearceJ

Due to the low number of trials with a low risk of bias and trials that implemented energy restriction alongside their intervention, we did not perform pre-specified sensitivity analyses with trials with a low risk of bias and energy restriction

Oral semaglutide versus subcutaneous liraglutide and placebo in type 2 diabetes (PIONEER 4): a randomised, double-blind, phase 3a trial

Prud'homme et al., 2015)
