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According to DermNet NZs resource on topical vitamin C, the compatibility of vitamin C with other actives is highly dependent on the specific form of vitamin C being used a point that reinforces why INKEYs choice of stabilised derivatives is so significant from a formulation standpoint

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An industry-sponsored trial from 2007 randomized 57 patients to verapamil, trifluoperazine (calmodulin-blocker) and magnesium sulfate (weak calcium channel blocker) (73)

This means you might be able to work harder without feeling as fatigued

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