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Our previous study demonstrated that a 14-day daily administration of lenvatinib to rats reduced OCTN2 protein levels in the skeletal muscle and intestine, but not in the kidney, and consequently decreased L-carnitine content in the skeletal muscle (Jing et al., 2022)

This suggests a time-dependent modulation of AmSOD1 isoforms, which likely helps manage oxidative stress during extended exposure to salt and lead toxicity

Steroids plus other immunomodulators (azathioprine or cyclosporine) were received by 31% of patients and were associated with 2.5 times increased chance of SNL than usage of steroids alone (in 18.5%)

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Foods 12 , 3784 (2023)

Assessment of brain structure in WD previously utilized computer-assisted axial tomography (or CT) scanning but now uses sophisticated MRI and advanced image manipulation