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In the heart, zinc enhances cardiac mitochondrial function during reperfusion by ERK-dependent phosphorylation of STAT3 at Ser727, which translocates to mitochondria to upregulate ND6 and inhibit succinate dehydrogenase, reducing ROS generation 152

Glutathione levels in antigen-presenting cells modulate Th1 versus Th2 response patterns

10.1002/ejhf.3347 24 SegarM

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A practical starting point before moving into more targeted therapies