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Pregnant women should use it only under clear necessity, while breastfeeding women are generally advised against its use

Despite the fact that meldonium is thought to be relatively safe and the number of side effects was found to be lower than 15% in clinical studies, 5 some potential complications have been reported, including 1 case of sudden death after peripheral embolism and ischaemic stroke (reported by a physician from the Russian Federation in a 69-year-old patient using multiple drugs other than meldonium), 1 case of multi-organ failure (reported by a health professional from Ukraine in a 74-year-old patient), along with additional cases of patients with diarrhoea, anaemia, fatigue, and serum bilirubin increase

Methods: We collected plasma samples and clinical data from 494 individuals with hyperlipidemia

Spaedy A, Doumas S, Solhkhah R

[DOI] [PubMed] [Google Scholar] 123.Davis J.M., Murphy E.A., Carmichael M.D., Zielinski M.R., Groschwitz C.M., Brown A.S., Gangemi J.D., Ghaffar A., Mayer E.P