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Mitochondria can also take up extracellular iron ions and transport them into their interior via specific transporters, where they are used for heme synthesis or stored in mitochondrial ferritin

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Nrf2 is a pivotal transcription factor associated with cellular anti-oxidant responses and serves as the central regulator for maintaining cellular redox homeostasis (Wang R

Reduced inflammation in the vascular endothelium helps to prevent endothelial dysfunction and atherosclerosis, which are critical in maintaining cardiovascular health [7,42,43]

A., Sidi S., Van Damme P., Benedetti C., et al

Group II metabotropic glutamate receptors in the striatum of non-human primates: dysregulation following chronic cocaine self-administration