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By 2030, the estimated number of AF/AFL-related deaths caused by lead exposure is approximately 11,880, with DALY cases reaching around 262,634 (Supplementary Figure S1)

In addition, we will discuss whether PDE5 inhibitors could be exploited for therapeutic purpose in cancer, evaluating ongoing clinical trials, summarized in Table 1

We next examined whether DNA methylation differences in the USCs correlated with RNA-seq fold changes in the differentiated urothelia between sensitized and resolved USCs, focusing on DMRs at promoter sites (Fig

Table 1 summarizes the expression changes of key ferroptosis-related molecules in COPD, their cell-specific localization, and functional outcomes

The mechanism diagram of attenuated Salmonella -mediated cancer therapy is shown in Figure 2

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