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Ismail et al., 2014

There were no differences between the two treatment groups in the change in BMD (p = 0.82) or BMC (p = 0.41)

An adjusted p -value 0.05 was considered a statistically significant result

If you develop signs of high cortisol like central weight gain despite overall weight loss, morning headaches, or mood disturbances, testing cortisol through saliva or 24-hour urine collection may be appropriate

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This can affect its stability and shelf-life