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The less-conserved transit peptide residues could be related with the functional diversities of GPXs at various targets

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One six-month, randomized, double-blinded, placebo-controlled trial [42] found that taking oral glutathione at either 250 or 1000 mg/day led to significant increases in the body stores of glutathione in 54 non-smoking adults in a dose-dependent manner

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The therapy helps patients feel an increase in energy the same day, while other benefits appear with repeated sessions

As hypoxia can be a mean of selecting more aggressive resistant cancer cells, we hypothesised that cysteine favours the adaptation to hypoxic conditions and chemotherapeutic agents, having a pivotal role in tumour progression, recurrence and chemoresistance