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Caution is advised in patients with Leber optic atrophy, a genetic disorder caused by chronic cyanide intoxication (such as from smoking, alcohol or some plants), against the use of cyano-B12 due to its cyanide moiety, whilst hydroxo-B12 is a cyanide antagonist and can therefore be used in these patients
10.3390/ijms19061736 69 LiY.LiX.LiX.ZengZ.StrangN.ShuX.et al (2022a)

Pathology of gestational choriocarcinoma induced in patas monkeys by ethylnitrosourea given during pregnancy
This article aims to evaluate the evidence relating to mitochondrial dysfunction in the pathogenesis of PVFS

doi: 10.1016/j.neuropharm.2014.08.019

doi: 10.1016/j.clinthera.2019.04.009 193 RocamondeBHasanUMathieuCDutartreH
