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While singly-housed animals may experience stress that impacts metabolism, body weight, and adiposity 65,66,67,68,69 , the singly-housed animals in this study were treated identically (to the best of the experimenters ability) to minimize and equalize stress across all animals and reduce confounding variables

It has been shown to significantly reduce visceral adipose tissue (VAT) in multiple randomized trials (NEJM/phase III evidence

2729 Pertinent downstream targets activated by Nox4-induced oxidants include NF-kappaB, ERK1/2, and mTORC1

The 3 molecules (glutathione, ascorbic acid and uric acid) were critical for Clostridi a survival since no growth was observed in aerobiosis without these molecules 17