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438 Functional MRI studies have reported augmented blood oxygen level-dependent (BOLD) responses in limbic and striatal structures in response to heat pain in PDPN patients

This pattern reflects the pulsatile release of GnRH and the corresponding waves of LH secretion that drive testosterone synthesis

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Furthermore, TFPs exhibit minimal side effects and are cost-effective, offering significant potential for future applications (54)

Side Effects and Acute Risks Hypoglycemia: Due to its insulin-like nature, IGF-DES may lower blood sugar, especially when used post-workout or without food