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Ophthalmic Res 33(4):196202 Kwon YH, Fingert JH, Kuehn MH, Alward WL (2009) Primary open-angle glaucoma

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Many studies have revealed that histone demethylases (HDMTs) are tightly related to drug resistance and regulated by inhibitors and siRNA, histone demethylases can modulate drug resistance by affecting multiple activities including autophagy, EMT and metabolism (Fig

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Importantly, several of these methylation sites also showed expression quantitative trait methylation effects, providing a direct link between epigenetic variation and transcriptomic output in islets

Stress On certain occasions, stress can affect the development of the intestinal barrier and be associated with increased gut permeability [69]
