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As these tolerant plants grow more vigorously at the initial stages due to more physiological adaptation than the cold-sensitive cultivars

Tolerability comparisons between retatrutide and tirzepatide are not 1:1 for that reason

This might explain the common x axis intercept in LineweaverBurk plots 11,17,18 , which resemble a non-competitive inhibition pattern with identical dissociation constants for the inhibitor and substrate 52