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The scoring standard for IHC staining adopted the immunoreactive score (IRS) system [15, 16], with the specific rules as follows: the staining intensity of GGCT protein was classified into four grades, where a score of 0 indicated no staining signal, 1 indicated weak positivity, 2 indicated moderate positivity, and 3 indicated strong positivity

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Stumped for an explanation, Eijkman asked his chicken coup caretaker if anything had changed in how the chickens are being cared for

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This kinase cascade is part of the broader MAP kinase signaling network that regulates cell proliferation, differentiation, and stress response pathways

10.1038/nm.3727 15 Changzhou Xinbo Longquan Wine Co., L (2003)