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''It wasn't really having an effect, but also the cost was a factor because there were other ingredients in the formulation that from a fat-reduction perspective were more effective,'' says Phosphagenics' chief scientific officer, Paul Gavin

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The only time you should be taking 5,000 to 10,000 micrograms a week is if you are treating B12 deficiency

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The slowed gastric emptying combined with altered gut motility creates unpredictable effects on colonic transit

The trials tested oral, intravenous, and subcutaneous routes of administration at doses ranging from micrograms to 1 mg per day