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Konstas AG, Schmetterer L, Katsanos A, Hutnik CML, Holl G, Quaranta L, Teus MA, Uusitalo H, Pfeiffer N, Katz LJ
These changes form the basis of the prooxidant state and lead to altered redox signaling related to glutathione deficiency and impaired expression and function of redox-sensitive transcriptional factors (Nrf2, NF- B, FoxO, etc.)
Orally bioavailable glutamine antagonist prodrug jhu-083 penetrates mouse brain and suppresses the growth of myc-driven medulloblastoma
Med 8 , 10921106 (2019)
[DOI] [PubMed] [Google Scholar] 103.Langston J.W
