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Coogan AN, Baird AL, Popa-Wagner A, Thome J

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doi.org/10.1038/s41467-023-36040-y 176

As with other areas of the body, oxidative stress and free radicals can cause premature aging

Pioglitazone confers neuroprotection against ischemia-induced pyroptosis due to its inhibitory effects on HMGB-1/RAGE and Rac1/ROS pathway by activating PPAR-

doi: 10.1016/j.freeradbiomed.2011.05.034
