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The morphological changes and biochemical processes that differentiate ferroptosis from other forms of programmed cell death are indicative of the unique characteristics of this process (Lee et al

doi: 10.1074/jbc.C300507200 [DOI] [PubMed] [Google Scholar] Zaki M., Thoenes M., Kawalia A., Nrnberg P., Kaiser R., Heller R., et al

394 NMR analysis showed that glutathione and N-acetylcysteine rapidly reduced the complexes to the reactive platinum(II) form via an inner-sphere mechanism similar to ormaplatin reduction

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Furthermore, in vivo xenograft transplantation of MHCC-97H cells have shown that number of pulmonary micrometastatic foci was significantly lowered in comparison to control group ( via inhibition of COX-2 and MMP-9, Ang-1, vasodilator-stimulated phosphoprotein (VASP) and VEGF (Noori-Daloii, 2012)
