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Sections of the L-thyroxine-treated group showed normal architecture of cardiac muscles with almost regular cardiomyocytes and some central oval vesicular nuclei (Figure 13e)

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In neurodegenerative conditions where fatty acid metabolism is impaired, the effective modulation of this pathway ensures efficient energy production from mitochondrial fatty acid oxidation [126]

Thus, TFG oligomerization mediated by the PB1 and CC domains enhances its PSAP-dependent interaction with TSG101, supporting a model in which oligomeric TFG within LASER accelerates ESCRT assembly on damaged lysosomes

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