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Compared to synthetically derived cannabinoids, naturally derived molecules induce few adverse effects and their use as promising and emerging therapeutic alternative has been investigated for treatment of several metabolic or neurodegenerative diseases (Sharma et al., 2015)

Cerebrospinal fluid, brain, and spinal cord levels of L-aspartate signal excitatory neurotransmission abnormalities in multiple sclerosis patients and experimental autoimmune encephalomyelitis mouse model

& Carrell, D

Lactate Levels (Mitochondrial Function): Serum lactate levels decreased significantly in the ALA group compared with placebo (6.45 mg/dL vs 2.27 mg/dL

Tan SY, Feng X, Cheng LKW, Wu AR

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