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Immunosenescence is associated with dysregulated signaling pathways (e.g., overactivation of the NF-B signaling pathway and downregulation of the melatonin signaling pathway) and abnormal immune cell responses with functional alterations and phenotypic shifts

Defective CD8 T cell responses in aged mice are due to quantitative and qualitative changes in virus-specific precursors

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Chen J., Zhang X., Kusumo H., et al., Cholesterol Efflux Is Differentially Regulated in Neurons and Astrocytes: Implications for Brain Cholesterol Homeostasis, Biochimica Et Biophysica Acta 1831, no