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326 In addition, the role of arginine methyltransferase (PRMT) in the regulation of tumorigenesis and development has also received extensive attention, and a variety of PRMT inhibitors have shown good anti-tumor activity in vitro and animal models, and a variety of drugs targeting type I PRMT and PRMT5 have been tested

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Combining IL-7 and IL-15 for T cell expansion Interleukin 7 (IL-7) is a cytokine required in early T cell development that promotes T cell survival by up-regulating the expression of anti-apoptotic genes

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Therefore, 250 L serum-free Opti-MEM media, 2.5 g respective pTM plasmid and 7.5 L Transit-LT1 were mixed and incubated at RT for 1530 min