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doi: 10.1002/jps.21924

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The short duration of effects promotes bingeing

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Treatment effects of cannabinoid combinations and cannabis extracts in Alzheimers disease Research suggests that cannabinoid treatments involving a combination of THC and CBD and other cannabinoids can produce greater therapeutic outcomes and less adverse effects than treatment with purified cannabinoid isolates

The nucleophile can also add to alpha,beta-unsaturated nitriles, such as in this example: The scope goes beyond alpha,beta unsaturated ketones and alpha,beta unsaturated nitriles to include alpha,beta unsaturated esters, nitro compounds, sulfonic esters and more