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Inducible suppression of NRF2 (tet_NRF2 KD ) decreased the expression of SLC7A11 but not of LDHB, as did LDHB KD, which reduced SLC7A11 but barely affected NRF2 expression ( Figure 6g )

Managing fatigue in sarcoidosis a systematic review of the evidence

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The predominant mechanism is attributed to its antioxidant properties that confer protection against oxidative damage, in an attempt to reestablish equilibrium in the respiratory tract