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The skin whitening treatment involves reducing the amount of melanin, the pigment that gives skin its color and achieve a brighter complexion.More melanin is present in people with darker complexions, and this pigment is what defines a persons skin colour

This review explores three key areas: (1) the biological mechanisms potentially linking NSW to BC, including melatonin suppression, oxidative stress, immune dysregulation, chronic inflammation, clock gene alterations, epigenetic modifications, telomere shortening, estrogen signaling disruption, vitamin D deficiency, and gut microbiome imbalance

The activities of antioxidant enzymes including SOD (particularly SOD2), CAT, GPx, and GR are markedly reduced, while oxidative stress markers such as malondialdehyde (MDA) and protein carbonylation levels are significantly increased (Xie et al., 2019)

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