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In vitro patch-clamp electrophysiology studies using TREK-1-expressing HEK293 cells have characterised the inhibitory potency and selectivity of PE-22-28 across the two-pore domain potassium channel family, examining whether the compound discriminates between TREK-1, TREK-2 and TRAAK subtypes

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Rosati, G., Maioli, M., Aiello, I., Farris, A

Conclusion Epitalon is a synthetic peptide that has generated interest for its potential effects on melatonin production, circadian rhythms, and other age-related biological processes

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