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These mice develop delayed aging features: progression of the age-related hearing loss is slowed down [89], and senile changes in the salivary glands are less pronounced [90]

Molecular reactions of protein phosphatases-insights from structure and chemistry

The exact pathophysiology remains incompletely understood but involves an exaggerated innate immune response and vasomotor instability leading to abnormal neurovascular signaling

ChakrabortyNPatraPKumarSAnindyaRGhosh AcharyyaS

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doi: 10.1016/j.biomaterials.2013.10.046