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Given that these studies utilized methods to assess dietary intake as a means of measuring vitamin B12 status, this may have resulted in an unreliable memory of individual dietary habits or errors in measurement, which could have influenced the final measurements of the aforementioned connections

Laboratory studies further underscore its potential for improving gut health, spinal cord injury recovery, chronic pain management, and cognitive function, suggesting possible future clinical applications

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It reduces methylationdriven consumption of NAM, increases substrate availability for NAD+ synthesis, and promotes NAD+ biosynthesis to elevate intracellular NAD+ levels

Reviewed by Natalie Punt, DVM This article was reviewed by Natalie Punt, DVM

29 Due to its importance in the synthesis of myelin and neurotransmitters, as well as in keeping homocysteine levels low, all of which are associated with cognitive function, B12 has been studied for a potential role in cognitive function