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ALDH2 activator AD-9308/AD-5591 lowered 4-HNE and attenuated diet-induced obesity, fatty liver, insulin resistance, and glucose intolerance in both WT and Aldh2 KI mice In view of the marked reduction in Aldh2 expression in diet-induced obese mice (Supplementary Fig

But is it as effective as these GLP1 drugs for weight loss
