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Bispecific T cell engagers for the treatment of multiple myeloma: achievements and challenges

GSTs function by conjugating reduced GSH and catalyzing the attack on foreign compounds or oxidative stress products, generally forming less-reactive materials that can be readily excreted

For example, the average axon length increased in diseased CSMN (prpTDP-43 A315T -UeGFP: 203.9 13.9 m, n = 3 mice, prpTDP-43 A315T -UeGFP + NMN: 372.8 15.8 m, n = 3 mice

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Initially, 1 H-MRS data were converted from the original time-domain format provided by the scanner to a frequency-domain GABA-edited spectrum using GannetLoad function

Similarly, S-allyl cysteine (SAC), an organic sulfur compound derived from garlic, demonstrates broad antioxidant and immunomodulatory effects by lowering ROS levels and inhibiting pro-inflammatory cytokines (e.g., IL-6 and myostatin), thus alleviating muscle atrophy (89)