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By contrast, the intranuclear amount of p65 of NF-B, which can suppress the gene expression of CYP1A2, CYP2E1, and CYP3A11, was higher in untreated IL-1ra KO than WT mice
Taken together, these new data demonstrate the complex interactions between NO, ROS signalling and the antioxidant system, although complementary investigations are needed to provide a global comprehension of this system
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