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Description
(1980) Inhibition of renal PGE 2 biosynthesis in vivo: regional differences
Journal of Immunology , 182 (6), 333541
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T.GontarzG
H 2 O 2 signaling leads to the release of Nrf2 from complexes with Kelch-like ECH-associated protein 1 (Keap1) and ubiquitin ligase Cullin 3 and into the nucleus, where it binds to antioxidant response elements (ARE) and activates the expression of its target gene GPX8, which in turn regulates the expression of ER calcium by regulating SERCA (Granatiero et al., 2019)
Interactions of zinc- and redox-signaling pathways
